Publications
Publication list from ISI Web of Knowledge Google Scholar Citations (You are welcome to email me to request publications for personal academic use)
Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes. J Geng#, K Kim#, J Zhang, A Escalada, R Tunuguntla, LR Comolli, FI Allen, AV Shnyrova, KR Cho, D Munoz, YM Wang, CP Grigopoulous, CM Ajo-Franklin, VA Frolov, A Noy*. Nature 514, pp 612-615 (2014)
Active DNA unwinding and transport by a membrane-adapted helicase nanopore. K Sun, C Zhao, X Zeng, Y Chen, X Jiang, X Ding, L Gou, H Xie, X Li, X Zhang, S Lin, L Dou, L Wei, H Niu, M Zhang, R Tian, E Sawyer, Q Yuan, Y Huang, P Chen, C Zhao, C Zhou, B Ying, B Shi, X Wei, R Jiang, L Zhang*, G Lu* , J Geng*. Nature Communications 10:5083 (2019)
[043] Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response. KLin JW#*, Tang C#, Wei HC#, Du B#, Chen C#, Wang M#, Zhou Y#, Yu MX#, Cheng L#, Kuivanen S#, Ogando NS, Levanov L, Zhao Y, Li CL, Zhou R, Li Z, Zhang Y, Sun K, Wang C, Chen L, Xiao X, Zheng X, Chen SS, Zhou Z, Yang R, Zhang D, Xu M, Song J, Wang D, Li Y, Lei S, Zeng W, Yang Q, He P, Zhang Y, Zhou L, Cao L, Luo F, Liu H, Wang L, Ye F, Zhang M, Li M, Fan W, Li X, Li K, Ke B, Xu J, Yang H, He S, Pan M, Yan Y, Zha Y, Jiang L, Yu C, Liu Y, Xu Z, Li Q, Jiang Y, Sun J, Hong W, Wei H, Lu G, Vapalahti O, Luo Y, Wei Y, Connor T, Tan W, Snijder EJ, Smura T*, Li W*, Geng J*, Ying B*, Chen L*. Cell Host & Microbe 29, 489-502 (2021)
[042] Homogeneous visual and fluorescence detection of circulating tumor cells in clinical samples via selective recognition reaction and enzyme-Free amplification. Chen P#, Wang Y#, He Y, Huang K, Wang X, Zhou R, Liu R, Qu R, Zhou J, Peng W, Li M, Bai Y, Chen J, Huang J, Geng J*, Xie Y*, Hu W*, Ying B*. ACS Nano doi:10.1021/acsnano.1c02080 (2021)
[041] Ultrasensitive nanopore sensing of mucin 1 and circulating tumor cells in whole blood of breast cancer patients by analytes-triggered triplex-DNA release. KSun K#, Chen P#, Yan SX#, Yuan WD, Wang Y, Li XQ, Dou LQ, Zhao CJ, Zhang JF, Wang Q, Fu ZK, Wei L, Xin ZD, Tang ZY, Yan YC, Peng YM, Ying BW, Chen J, Geng J*. ACS Applied Materials & Interfaces (2021)
[040] Structure and unzipping behavior of dumbbell and hairpin DNA revealed by real-time nanopore sensing. Li X, Song G, Dou L, Yan S, Zhang M, Yuan W, Lai S, Jiang X, Li K, Sun K, Zhao C, Geng J*. Nanoscale doi:10.1039/d0nr08729g (2021)
[039] Low-Cost and Scalable Platform with Multiplexed Microwell Array Biochip for Rapid Diagnosis of COVID-19. Wang Y#, Li K#, Xu G#, Chen C, Song G, Dong Z, Lin L, Wang Y, Xu Z, Yu M, Yu X, Ying B*, Fan Y*, Chang L*, Geng J*. Research doi: 10.34133/2021/2813643 (2021)
[038] Visual and dual-fluorescence homogeneous sensor for the detection of pyrophosphatase in clinical hyperthyroidism samples based on selective recognition of CdTe QDs and coordination polymerization of Ce3+. Chen PP, Qu RL, Wu P, Wang X, Huang K, He YQ, Zhang XL, Meng YM, Liu TYH, Chen J, Xie Y, Huang J, Hu Q*, Geng J*, Ying BW*. Journal of Materials Chemistry C , 4141-4149 (2021)
[037] Real-time sensing of neurotransmitters by functionalized nanopores embedded in a single live cell. Zhang XL, Dou LQ, Zhang M, Wang Y, Jiang X, Li XQ, Wei L, Chen YJ, Zhou CS & Geng J*. Molecular Biomedicine article number: 6 (2021) doi: 10.1186/s43556-021-00026-3
[036] A designed locked nucleic acid-based nanopore for discriminating ctDNA and its coexisting analogue ncDNA. H YQ, Lv You, Geng J, Xiao D, Zhou C*. Chinese Chemical Letters 31, 172-176 (2021)
[035] Single‐Molecule Interaction of Peptides with a Biological Nanopore for Identification of Protease Activity. K Sun, C Zhao, X Zeng, Y Chen, X Jiang, X Ding, L Gou, H Xie, X Li, X Zhang, S Lin, L Dou, L Wei, H Niu, M Zhang, R Tian, E Sawyer, Q Yuan, Y Huang, P Chen, C Zhao, C Zhou, B Ying, B Shi, X Wei, R Jiang, L Zhang*, G Lu* , J Geng*. Small Methods doi:10.1002/smtd.201900892 (2020)
[034] Structural basis for gating mechanism of Pannexin 1 channel. Mou L#, Ke M#, Song M#, Shan Y#, Xiao Q, Liu Q, Li J, Sun K, Pu L, Guo L, Geng J*, Wu J*, Deng D*. Cell Research doi: 10.1038/s41422-020-0313-x (2020)
[033] Detection of Circulating Tumor Cells in Breast Cancer Patients by Nanopore Sensing with Aptamer-Mediated Amplification. Li X#, Zhang P#, Dou L, Wang Y, Sun K, Zhang X, Song G, Zhao C, Li K, Bai Y, Zeng X, Zhou C, Ying B*, Chen J*, Geng J*. Detection of Circulating Tumor Cells in Breast Cancer Patients by Nanopore Sensing with Aptamer-Mediated Amplification. ACS Sensors doi: 10.1021/acssensors.9b02537 (2020)
[032] Rapid and highly sensitive visual detection of oxalate for metabolic assessment of urolithiasis via selective recognition reaction of CdTe quantum dots. P Chen, Y Bai, Y Tang, S Yan, X Wang, W Wei, J Wang, M Zhang, B Ying and J Geng*. Journal of Materials Chemistry B doi:10.1039/D0TB01108H (2020)
[031] Development of a fluorescent DNA nanomachine for ultrasensitive detection of Salmonella enteritidis without labeling and enzymes. Zhang P#, Song M#, Dou L#, Xiao Y, Li K, Shen G, Ying B, Geng J*, Yang D*, Wu Z*. Mikrochim Acta. 187(7):376. (2020)
[030] Thiol inhibition of Hg cold vapor generation in SnCl2/NaBH4 system: A homogeneous bioassay for H2O2/glucose and butyrylcholinesterase/pesticide sensing by atomic spectrometry. Chen P, Zheng C, Chen C, Huang K, Wang X, Hu P, Geng J*. Analytica Chimica Acta doi: 10.1038/s41422-020-0313-x (2020)
[029] Active DNA unwinding and transport by a membrane-adapted helicase nanopore. K Sun, C Zhao, X Zeng, Y Chen, X Jiang, X Ding, L Gou, H Xie, X Li, X Zhang, S Lin, L Dou, L Wei, H Niu, M Zhang, R Tian, E Sawyer, Q Yuan, Y Huang, P Chen, C Zhao, C Zhou, B Ying, B Shi, X Wei, R Jiang, L Zhang*, G Lu* , J Geng*. Nature Communications 10: 5083 (2019)
[028] Opportunities and challenges for nanopore⁃based clinical diagnostics. C Zhao, B Ying, J Geng*. Chinese Journal of Laboratory Medicine 42, 827-830 (2019)
[027] Rapid Nanopore Assay for Carbapenem-Resistant Klebsiella pneumoniae. H Niu, W Zhang, L Wei, M Liu, H Liu, C Zhao, P Zhang, Q Liao, Y Liu, Q Yuan, S Wu, M Kang*, J Geng*. Frontiers in Microbiology. 10:1672 (2019)
[026] A general strategy for label-free homogeneous bioassays based on selective recognition and silver ion-mediated conformational switch. P Chen, X Jiang, K Huang, J Geng*. ACS Applied Materials & Interfaces 11, 36476−36484 (2019)
[025] Exonuclease III-assisted strand displacement reaction-driven cyclic generation of G-quadruplex strategy for homogeneous fluorescent detection of melamine. P Chen, K Huang, P Zhang, E Sawyer, Z Wu, X Wei, B Ying, Z Wu*, J Geng*. Talanta 203, 255-260 (2019)
[024] A general strategy for label-free homogeneous bioassays based on selective recognition and silver ion-mediated conformational switch. P Chen, E Sawyer, K Sun, X Zhang, C Chen, B Ying, X Wei, Z Wu*, J Geng*. Talanta 201, 9-15 (2019)
[023] Sensitive CVG-AFS/ICP-MS label-free nucleic acid and protein assays based on a selective cation exchange reaction and simple filtration separation. P Chen, K Huang, R Dai, E Sawyer, K Sun, B Ying, X Wei, Z Wu*, J Geng*. Analyst 144, 2797-2802 (2019)
[022] Rapid and simple detection of ascorbic acid and alkaline phosphatase via controlled generation of silver nanoparticles and selective recognition. P Chen, S Yan, E Sawyer, B Ying, X Wei, Z Wu*, J Geng*. Analyst 144, 1147-1152 (2018)
[021] Detection of nucleic acids via G-quadruplex-controlled L-cysteine oxidation and catalyzed hairpin assembly-assisted signal amplification. P Chen P, P Hu, K Huang, E Sawyer, K Sun, B Ying, X Wei X, J Geng*. RSC Advances 8, 40564-40569 (2018)
[020] Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel. P Sun#, J Li#, X Zhang#, Z Guan, Q Xiao, C Zhao, M Song, Y Zhou, L Mou, M Ke, L Guo, J Geng*, D Deng*. J. Biol. Chem. 293, 19492-19500 (2018)
[019] Effective and targeted human orthotopic glioblastoma xenograft therapy via a multifunctional biomimetic nanomedicine. Y Zou#, Y Liu#, Z Yang, D Zhang, Y Lu, M Zheng*, X Xue, J Geng, R Chung, B Shi*. Advanced Materials 51, e1803717 (2018)
[018] Hyaluronan reduces cationic liposome-induced toxicity and enhances the antitumour effect of targeted gene delivery in mice. Y Qian#, X Liang#, J Yang, C Zhao, W Nie, L Liu, T Yi, Y Jiang, J Geng, X Zhao, X Wei*. ACS Appl. Mater. Interfaces 10, 32006–32016 (2018)
[017] Negative regulation of cationic nanoparticle-induced inflammatory toxicity through the increased production of prostaglandin E2 via mitochondrial DNA-activated Ly6C+ monocytes. L Liu#, Y Liu#, B Xu, C Liu, Y Jia, T Liu, C Fang, W Wang, J Ren, Z He, K Men, X Liang, M Luo, B Shao, Y Mao, H Xiao, Z Qian, J Geng, B Dong, P Mi, Y Jiang, Y Wei, X Wei* Theranostics 8, 3138-3152 (2018)
[016] Simultaneous discrimination of single-base mismatch and full match using a label-free single-molecule strategy. Q Yang, T Ai, Y Lv, Y Huang, J Geng, D Xiao, C Zhou* Analytical Chemistry 90, 8102–8107 (2018)
[015] Insight into how telomeric G‐quadruplex enhance the peroxidase activity of cellular hemin. T Ai, Q Yang, Y Lv, Y Huang, Y Li, J Geng, D Xiao, C Zhou* Chem. Asian J. 13, 1805-1810 (2018)
[014] Single-molecule investigation of human telomeric G-quadruplex interactions with Thioflavin T. H Cai, C Zhou*, Q Yang, T Ai, Y Huang, Y Lv, J Geng, D Xiao* Chinese Chemical Letters 29, 531-534 (2017)
[013] Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development. PW He, M Felderman, AC Evans, J Geng, D Homan, F Bourguet, NO Fischer, Y Li, KS Lam, A Noy, L Xing, RH Cheng, A Rasley, CD Blanchette, K Kamrud, N Wang, H Gouvis, TC Peterson, B Hubby, MA Coleman* J. Biol. Chem. 292, 15121-15132 (2017)
[012] Novel wound dressing based on nanofibrous PHBV–keratin mats. J Yuan, J Geng, Z Xing, KJ Shim, I Han, JC Kim, IK Kang*, J Shen*. Journal of Tissue Engineering and Regenerative Medicine 9, 1027-1035 (2015)
[011] Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes. J Geng#, K Kim#, J Zhang, A Escalada, R Tunuguntla, LR Comolli, FI Allen, AV Shnyrova, KR Cho, D Munoz, YM Wang, CP Grigopoulous, CM Ajo-Franklin, VA Frolov, A Noy*. Nature 514, pp 612-615 (2014)
[010] Osmotically-driven transport in carbon nanotube porins. K Kim, J Geng, R Tunuguntla, LR Comolli, CP Grigopoulous, CM Ajo-Franklin, A Noy*. Nano Letters 14, 7051–7056 (2014)
[009] Channel size conversion of phi29 DNA-packaging nanomotor for discrimination of single- and double-stranded nucleic acids. J Geng, S Wang, H Fang, P Guo*. ACS Nano 7, 3315–3323 (2013)
[008] Incorporation of a viral DNA-packaging motor channel in lipid bilayers for real-time, single-molecule sensing of chemicals and double-stranded DNA. F Haque, J Geng, C Montemagno, P Guo*. Nature Protocols 8, 373-392 (2013)
[007] Formation of lipid bilayers inside microfluidic channel array for monitoring membrane-embedded nanopores of phi29 DNA packagingnanomotor. JS Shim, J Geng, CH Ahn, P Guo*. Biomedical Microdevices 14, 921-928 (2012)
[006] Membrane-embedded channel of bacteriophage phi29 DNA-packaging motor for single molecule sensing and nanomedicine. J Geng, P Guo*. Chinese Bulletin of Life Sciences 23, 1114-1129 (2011)
[005] Three reversible and controllable discrete steps of channel gating of a viral DNA packaging motor. J Geng, H Fang, F Haque, L Zhang, P Guo*. (2011) Biomaterials 32, 8234–8242. (2011)
[004] Versatile DNA packaging nanomotor of bacteriophage phi29 with applications in nanobiotechnology. J Geng, AP Vonderheide*. Nano LIFE 1, 45-62 (2010)
[003] Electrospinning of antibacterial poly (vinylidene fluoride) nanofibers containing silver nanoparticles. J Yuan, J Geng, Z Xing, J Shen, IK Kang*, H Byun. Journal of Applied Polymer Science 116, 668-672 (2009)
[002] Fabrication of PHBV/keratin composite nanofibrous mats for biomedical applications. J Yuan, ZC Xing, SW Park, J Geng, IK Kang*, J Yuan, J Shen, W Meng, KJ Shim, IS Han, JC Kim. Macromolecular Research 17, 850-855 (2009)
[001] Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanopores. D Wendell, P Jing, J Geng, V Subramaniam, TJ Lee, C Montemagno, P Guo*. Nature Nanotechnology 4, 765-772 (2009)